Spotlights Series

22 May, 2025

Dr Siyan Yi: Developing and piloting infection prevention and control intervention to reduce the incidence of hospital-acquired infection in Cambodia and Lao PDR

This week, we’re highlighting the work of Dr. Siyan Yi, an RGHI Innovation Grant Award Holder, whose research addresses the critical challenges of hospital-acquired infections (HAIS) in Cambodia and Lao PDR. Working with co-Principal Investigators Dr. Vonthanak Saphonn and Dr. Somphu Sayasone, Dr. Yi’s team is developing tailored infection prevention and control (IPC) interventions to reduce the burden of these often-overlooked infections in healthcare settings.  

Hospital-acquired infections pose a significant threat to public health, especially in low and middle-income countries. Many “nosocomial” infections receive limited attention, specifically from policymakers, unless there is an epidemic, such as the COVID-19 pandemic, which demonstrated the effectiveness of enhanced infection prevention and control (IPC) measures in healthcare settings and the importance of basic hygiene and healthcare for public health.

These infections disproportionately affect low and middle-income countries (LMICs) where their economic burdens exceed those of high-income nations, highlighting the importance of effective prevention programs.

The research project consists of three key components:

  • Gap analysis of the current IPC implementation and practices among healthcare workers at different facility levels.
  • Development of targeted IPC interventions based on identified gaps and evidence from systematic reviews.
  • Pilot implementation and evaluation to assess feasibility and acceptability in Cambodia and Lao PDR.

This research builds upon the World Health Organisation guidelines, which address specific challenges in these countries. By developing interventions that are contextually appropriate for LMICS, this research creates solutions that can be effectively implemented.  The findings will be shared through dissemination workshops with policymakers and stakeholders presented at various forums and published in peer-reviewed journals to inform IPC efforts worldwide.

This research exemplifies practical solutions that RGHI is committed to supporting. The potential for this work to be scaled across other low and middle-income countries makes it even more valuable for global public health.

  • Sarah Roberts, RGHI Executive Director  

The RGHI Spotlight Series showcases researchers’ inspiring work on improving global hygiene and health outcomes. Each post highlights a project funded through an RGHI grant or fellowship, detailing its goals, progress, and potential impact. These spotlights celebrate innovation and collaboration in tackling some of the world’s most pressing hygiene challenges. To learn more about RGHI-funded research and its contributions to advancing hygiene and health worldwide, explore our research portfolio.

Stay tuned for more next week and keep up to date with the latest RGHI news on LinkedIn and BlueSky.